<p>This entry represents a structural domain with a core fold consisting of alpha-beta(2)-(alpha-beta)2 that folds into three layers, a/b/a; some members may contain an extra C-terminal strand. This domain is found in several types of proteins, including:</p><p> <ul><li>Cytidine deaminase (<db_xref db="EC" dbkey="3.5.4.5"/>), including both mono-domain enzymes [<cite idref="PUB00027416"/>] and two-domain enzymes that arose through a duplication and which contain extra helices in the N-terminal domain [<cite idref="PUB00028183"/>].</li><li>Deoxycytidylate (dCMP) deaminase (<db_xref db="EC" dbkey="3.5.4.12"/>) [<cite idref="PUB00032117"/>].</li><li>Guranine deaminase GuaD (<db_xref db="EC" dbkey="3.5.4.3"/>) [<cite idref="PUB00032259"/>].</li><li>Cytosine deaminase (<db_xref db="EC" dbkey="3.5.4.1"/>) [<cite idref="PUB00042648"/>].</li><li>AICAR transformylase domain (<db_xref db="EC" dbkey="2.1.2.3"/>) of the bifunctional purine biosynthesis enzyme ATIC; this protein consists of two domains of this fold with extra secondary structures within and in between the two core motifs [<cite idref="PUB00025174"/>].</li><li>Hypothetical protein TM1506 from <taxon tax_id="2336">Thermotoga maritima</taxon> also contains a domain of this structure.</li></ul> </p> Cytidine deaminase-like